![\"Legs](\"https:\/\/i0.wp.com\/thepublicationplan.com\/wp-content\/uploads\/2019\/03\/COMPare.jpg?resize=1254%2C836&ssl=1\")
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Guidance from the EQUATOR network<\/a> and the ICMJE<\/a> stipulates that clinical trials must be publicly registered at inception in order for results to be considered for publication. This practice was intended to reduce selective reporting of trial outcomes; however, discrepancies between pre-specified and published outcomes of clinical trials persist<\/a>. A recent article<\/a> published in Trials<\/a><\/em> by Dr Ben Goldacre (AllTrials<\/a>-founder) and colleagues reported high levels of outcome misreporting in journals listed as endorsing the CONSORT statement<\/a> on the correct reporting of clinical trials. What\u2019s more, the group reported that most correction letters they sent to address such misreporting were rejected.<\/p>\n This prospective study (COMPare<\/a>) tracked outcome switching in 67 randomised controlled trials (RCTs) published over a six-week period (19 Oct\u201330 Nov 2015) in the five top CONSORT-endorsing medical journals (The New Engl J Med<\/a><\/em>, The Lancet<\/a><\/em>, JAMA<\/a><\/em>, The BMJ<\/a><\/em> and Annals of Internal Medicine<\/a><\/em>). Overall, outcome reporting was deemed to be poor; 58\/67 (87%) manuscripts analysed contained CONSORT-breaching discrepancies judged to require a correction letter. Of these letters, only 40% were published, with a median delay of 99 days. Qualitative analysis<\/a> was thought to suggest misunderstanding among journal editors surrounding correct outcome reporting and CONSORT, a finding that may explain why some journals did not cooperate when presented with evidence of misreporting.<\/p>\n The authors warn that readers of a journal with a CONSORT-supporting stance may assume that trial results are reported in line with pre-specified outcomes. To ensure this is the case, Goldacre and his colleagues suggest a number of strategies: 1) Changes to journals\u2019 correspondence processes; 2) Indexed post-publication peer review; 3) Changes to CONSORT\u2019s enforcement mechanisms; 4) Changes to practices in methodology research to increase sharing of misreporting with the broader academic community.<\/p>\n \u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2013<\/p>\n Summary by\u00a0Emma Prest PhD<\/a>\u00a0from\u00a0Aspire Scientific<\/a><\/p>\n \u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2014\u2013<\/p>\n With thanks to our sponsors, Aspire Scientific Ltd<\/a> and NetworkPharma Ltd<\/a><\/p>\n Selective reporting of clinical trial outcomes may be widespread. This study reports instances occurring in CONSORT-endorsing medical journals.<\/p>\n","protected":false},"author":4,"featured_media":5689,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_publicize_connection_overrides":[],"_wpas_customize_per_network":false},"categories":[231660481,9631846,322948647,16950752],"tags":[343162440,343162404,343162406],"class_list":["post-5688","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-clinical-trial-registries","category-reporting-guidelines","category-selective-publication","category-data-transparency","tag-academic-publishing","tag-consort","tag-randomised-controlled-trial-rct","post-has-thumbnail"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/thepublicationplan.com\/wp-content\/uploads\/2019\/03\/COMPare.jpg?fit=1254%2C836&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5Yk5l-1tK","jetpack_likes_enabled":true,"jetpack-related-posts":[],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/thepublicationplan.com\/wp-json\/wp\/v2\/posts\/5688","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/thepublicationplan.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/thepublicationplan.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/thepublicationplan.com\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/thepublicationplan.com\/wp-json\/wp\/v2\/comments?post=5688"}],"version-history":[{"count":2,"href":"https:\/\/thepublicationplan.com\/wp-json\/wp\/v2\/posts\/5688\/revisions"}],"predecessor-version":[{"id":5691,"href":"https:\/\/thepublicationplan.com\/wp-json\/wp\/v2\/posts\/5688\/revisions\/5691"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/thepublicationplan.com\/wp-json\/wp\/v2\/media\/5689"}],"wp:attachment":[{"href":"https:\/\/thepublicationplan.com\/wp-json\/wp\/v2\/media?parent=5688"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/thepublicationplan.com\/wp-json\/wp\/v2\/categories?post=5688"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/thepublicationplan.com\/wp-json\/wp\/v2\/tags?post=5688"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}<\/div>\n
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